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Irene Lecker
Irene Lecker
Verified email at utoronto.ca
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Year
Tranexamic acid–associated seizures: causes and treatment
I Lecker, DS Wang, PD Whissell, S Avramescu, CD Mazer, BA Orser
Annals of neurology 79 (1), 18-26, 2016
2652016
Proteomic analysis of seminal plasma from normal volunteers and post-vasectomy patients identifies over 2000 proteins and candidate biomarkers of the urogenital system
I Batruch, I Lecker, D Kagedan, CR Smith, BJ Mullen, E Grober, KC Lo, ...
Journal of proteome research 10 (3), 941-953, 2011
1952011
Sustained increase in α5GABAA receptor function impairs memory after anesthesia
AA Zurek, J Yu, DS Wang, SC Haffey, EM Bridgwater, A Penna, I Lecker, ...
The Journal of clinical investigation 124 (12), 5437-5441, 2014
1942014
Tranexamic acid concentrations associated with human seizures inhibit glycine receptors
I Lecker, DS Wang, AD Romaschin, M Peterson, CD Mazer, BA Orser
The Journal of clinical investigation 122 (12), 4654-4666, 2012
1862012
Memory deficits induced by inflammation are regulated by α5-subunit-containing GABAA receptors
DS Wang, AA Zurek, I Lecker, J Yu, AM Abramian, S Avramescu, ...
Cell reports 2 (3), 488-496, 2012
1822012
Altered expression of δGABAA receptors in health and disease
PD Whissell, I Lecker, DS Wang, J Yu, BA Orser
Neuropharmacology 88, 24-35, 2015
792015
Cause-specific treatment in patients with high sperm DNA damage resulted in significant DNA improvement
SI Moskovtsev, I Lecker, JBM Mullen, K Jarvi, J Willis, J White, KC Lo
Systems Biology in Reproductive Medicine 55 (2-3), 109-115, 2009
772009
Small incidentally discovered testicular masses in infertile men—is active surveillance the new standard of care?
PJ Toren, M Roberts, I Lecker, ED Grober, K Jarvi, KC Lo
The Journal of urology 183 (4), 1373-1377, 2010
722010
Acutely increasing δGABAA receptor activity impairs memory and inhibits synaptic plasticity in the hippocampus
PD Whissell, D Eng, I Lecker, LJ Martin, DS Wang, BA Orser
Frontiers in neural circuits 7, 146, 2013
602013
Frequency and severity of sperm DNA damage in patients with confirmed cases of male infertility of different aetiologies
SI Moskovtsev, JBM Mullen, I Lecker, K Jarvi, J White, M Roberts, KC Lo
Reproductive biomedicine online 20 (6), 759-763, 2010
602010
Dexmedetomidine prevents excessive γ-aminobutyric acid type A receptor function after anesthesia
DS Wang, K Kaneshwaran, G Lei, F Mostafa, J Wang, I Lecker, ...
Anesthesiology 129 (3), 477-489, 2018
552018
γ‐aminobutyric acid type A receptors that contain the δ subunit promote memory and neurogenesis in the dentate gyrus
PD Whissell, S Rosenzweig, I Lecker, DS Wang, JM Wojtowicz, BA Orser
Annals of neurology 74 (4), 611-621, 2013
482013
Inflammation increases neuronal sensitivity to general anesthetics
S Avramescu, DS Wang, I Lecker, WTH To, A Penna, PD Whissell, ...
Anesthesiology 124 (2), 417-427, 2016
442016
Cage-lid hanging behavior as a translationally relevant measure of pain in mice
H Zhang, I Lecker, C Collymore, A Dokova, MC Pham, SF Rosen, ...
Pain 162 (5), 1416-1425, 2021
412021
Potentiation of GABAA receptor activity by volatile anaesthetics is reduced by α5GABAA receptor-preferring inverse agonists
I Lecker, Y Yin, DS Wang, BA Orser
British journal of anaesthesia 110 (suppl_1), i73-i81, 2013
412013
Evaluating analgesic efficacy and administration route following craniotomy in mice using the grimace scale
C Cho, V Michailidis, I Lecker, C Collymore, D Hanwell, M Loka, ...
Scientific reports 9 (1), 359, 2019
402019
α5GABAA Receptors Mediate Tonic Inhibition in the Spinal Cord Dorsal Horn and Contribute to the Resolution Of Hyperalgesia
J Perez‐Sanchez, LE Lorenzo, I Lecker, AA Zurek, C Labrakakis, ...
Journal of neuroscience research 95 (6), 1307-1318, 2017
402017
Characterization of the seminal plasma proteome in men with prostatitis by mass spectrometry
D Kagedan, I Lecker, I Batruch, C Smith, I Kaploun, K Lo, E Grober, ...
Clinical proteomics 9, 1-20, 2012
362012
Effect of multiple doses of oral tranexamic acid on haemostasis and inflammatory reaction in total hip arthroplasty: a randomized controlled trial
D Wang, Y Yang, C He, ZY Luo, FX Pei, Q Li, ZK Zhou, WN Zeng
Thrombosis and Haemostasis 119 (01), 092-103, 2019
332019
Hydrogen peroxide increases GABAA receptor-mediated tonic current in hippocampal neurons
A Penna, DS Wang, J Yu, I Lecker, PMGE Brown, D Bowie, BA Orser
Journal of Neuroscience 34 (32), 10624-10634, 2014
312014
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