Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS ET Chouchani, VR Pell, E Gaude, D Aksentijević, SY Sundier, EL Robb, ... Nature 515 (7527), 431-435, 2014 | 2456 | 2014 |
Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway H Ashrafian, G Czibik, M Bellahcene, D Aksentijević, AC Smith, ... Cell metabolism 15 (3), 361-371, 2012 | 298 | 2012 |
Selective superoxide generation within mitochondria by the targeted redox cycler MitoParaquat EL Robb, JM Gawel, D Aksentijević, HM Cochemé, TS Stewart, ... Free Radical Biology and Medicine 89, 883-894, 2015 | 128 | 2015 |
Living without creatine: unchanged exercise capacity and response to chronic myocardial infarction in creatine-deficient mice CA Lygate, D Aksentijevic, D Dawson, M Ten Hove, D Phillips, ... Circulation research 112 (6), 945-955, 2013 | 116 | 2013 |
Moderate elevation of intracellular creatine by targeting the creatine transporter protects mice from acute myocardial infarction CA Lygate, S Bohl, M ten Hove, KME Faller, PJ Ostrowski, S Zervou, ... Cardiovascular research 96 (3), 466-475, 2012 | 93 | 2012 |
Structural basis for a complex I mutation that blocks pathological ROS production Z Yin, N Burger, D Kula-Alwar, D Aksentijević, HR Bridges, HA Prag, ... Nature communications 12 (1), 707, 2021 | 85 | 2021 |
Mechanism of succinate efflux upon reperfusion of the ischaemic heart HA Prag, AV Gruszczyk, MM Huang, TE Beach, T Young, L Tronci, ... Cardiovascular research 117 (4), 1188-1201, 2021 | 77 | 2021 |
On the pivotal role of PPARα in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury MA Cole, AH Abd Jamil, LC Heather, AJ Murray, ER Sutton, M Slingo, ... The faseb journal 30 (8), 2684, 2016 | 70 | 2016 |
Increased oxidative metabolism following hypoxia in the type 2 diabetic heart, despite normal hypoxia signalling and metabolic adaptation LS Mansor, K Mehta, D Aksentijevic, CA Carr, T Lund, MA Cole, LL Page, ... The Journal of physiology 594 (2), 307-320, 2016 | 53 | 2016 |
Artificial intelligence in cardiology: Hope for the future and power for the present L Karatzia, N Aung, D Aksentijevic Frontiers in Cardiovascular Medicine 9, 945726, 2022 | 50 | 2022 |
Intracellular sodium elevation reprograms cardiac metabolism D Aksentijević, A Karlstaedt, MV Basalay, BA O’Brien, D Sanchez-Tatay, ... Nature communications 11 (1), 4337, 2020 | 50 | 2020 |
Impaired cardiac contractile function in arginine: glycine amidinotransferase knockout mice devoid of creatine is rescued by homoarginine but not creatine KME Faller, D Atzler, DJ McAndrew, S Zervou, HJ Whittington, JN Simon, ... Cardiovascular research 114 (3), 417-430, 2018 | 43 | 2018 |
Ischemia-selective cardioprotection by malonate for ischemia/reperfusion injury HA Prag, D Aksentijevic, A Dannhorn, AV Giles, JF Mulvey, O Sauchanka, ... Circulation research 131 (6), 528-541, 2022 | 36 | 2022 |
Unchanged mitochondrial organization and compartmentation of high-energy phosphates in creatine-deficient GAMT−/− mouse hearts J Branovets, M Sepp, S Kotlyarova, N Jepihhina, N Sokolova, ... American Journal of Physiology-Heart and Circulatory Physiology 305 (4 …, 2013 | 36 | 2013 |
High‐energy phosphotransfer in the failing mouse heart: role of adenylate kinase and glycolytic enzymes D Aksentijević, CA Lygate, K Makinen, S Zervou, L Sebag‐Montefiore, ... European journal of heart failure 12 (12), 1282-1289, 2010 | 36 | 2010 |
Multiple quantum filtered 23Na NMR in the Langendorff perfused mouse heart: Ratio of triple/double quantum filtered signals correlates with [Na] i TR Eykyn, D Aksentijević, KL Aughton, R Southworth, W Fuller, ... Journal of Molecular and Cellular Cardiology 86, 95-101, 2015 | 32 | 2015 |
Cardiac metabolic remodelling in chronic kidney disease N Patel, MM Yaqoob, D Aksentijevic Nature Reviews Nephrology 18 (8), 524-537, 2022 | 29 | 2022 |
Insulin resistance and altered glucose transporter 4 expression in experimental uremia D Aksentijević, S Bhandari, AML Seymour Kidney international 75 (7), 711-718, 2009 | 29 | 2009 |
Cardiac metabolomic profile of the naked mole-rat—glycogen to the rescue CG Faulkes, TR Eykyn, D Aksentijevic Biology letters 15 (11), 20190710, 2019 | 28 | 2019 |
Chronic creatine kinase deficiency eventually leads to congestive heart failure, but severity is dependent on genetic background, gender and age CA Lygate, DJ Medway, PJ Ostrowski, D Aksentijevic, L Sebag-Montefiore, ... Basic research in cardiology 107, 1-11, 2012 | 28 | 2012 |